Pupillary Light Reaction during High Altitude Exposure

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Pupillary Light Reaction during High Altitude Exposure

PURPOSE This study aimed to quantify the pupillary light reaction during high altitude exposure using the state of the art Compact Integrated Pupillograph (CIP) and to investigate a potential correlation of altered pupil reaction with severity of acute mountain sickness (AMS). This work is related to the Tübingen High Altitude Ophthalmology (THAO) study. METHODS Parameters of pupil dynamics (...

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Pupillary diameter and reaction to light in preterm neonates.

The pupil controls the amount of light entering the eye. We have examined both the time course for the development of the light reflex and pupil diameter before and after this event in 50 neonates. The pupillary light reflex was absent in all neonates of less than 30 weeks' gestational age, it gradually developed from this age and by 35 weeks it was present in all. Several possible mechanisms t...

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Pupillary diameter and reaction to light in preterm

The pupil controls the amount of light entering the eye. We have examined both the time course for the development of the light reflex and pupil diameter before and after this event in 50 neonates. The pupillary light reflex was absent in ali neonates of less than 30 weeks' gestational age, it graduafly developed from this age and by 35 weeks it was present in all. Several possible mechanisms t...

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Augmented sympathetic activation during short-term hypoxia and high-altitude exposure in subjects susceptible to high-altitude pulmonary edema.

BACKGROUND Pulmonary hypertension is a hallmark of high-altitude pulmonary edema and may contribute to its pathogenesis. Cardiovascular adjustments to hypoxia are mediated, at least in part, by the sympathetic nervous system, and sympathetic activation promotes pulmonary vasoconstriction and alveolar fluid flooding in experimental animals. METHODS AND RESULTS We measured sympathetic nerve act...

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Melanopsin and rod-cone photoreceptors play different roles in mediating pupillary light responses during exposure to continuous light in humans.

In mammals, the pupillary light reflex is mediated by intrinsically photosensitive melanopsin-containing retinal ganglion cells that also receive input from rod-cone photoreceptors. To assess the relative contribution of melanopsin and rod-cone photoreceptors to the pupillary light reflex in humans, we compared pupillary light responses in normally sighted individuals (n = 24) with a blind indi...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0087889